The SMAL web server: global multiple network alignment from pairwise alignments
نویسندگان
چکیده
منابع مشابه
Pairwise versus multiple network alignment
Motivation: Network alignment (NA) can be pairwise (PNA) and multiple (MNA). PNA produces aligned node pairs between two networks. MNA produces aligned node clusters between more than two networks. Recently, the focus has shied from PNA to MNA, because MNA captures conserved regions between more networks than PNA (and MNA is thus considered to be more insightful), though at higher computationa...
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UNLABELLED Alignment-Annotator is a novel web service designed to generate interactive views of annotated nucleotide and amino acid sequence alignments (i) de novo and (ii) embedded in other software. All computations are performed at server side. Interactivity is implemented in HTML5, a language native to web browsers. The alignment is initially displayed using default settings and can be modi...
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A necessity of repeating alignments on a same pair of sequences to select an appropriate scoring function to detect a significance of score motivates us to work on higher performance matching technique. While overlapping each alignments obtained through a set of typical scoring matrix with its default gap cost, we observe significant parameters that may induce a maximum deviation from a referen...
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MOTIVATION Multiple sequence alignment is a fundamental task in bioinformatics. Current tools typically form an initial alignment by merging subalignments, and then polish this alignment by repeated splitting and merging of subalignments to obtain an improved final alignment. In general this form-and-polish strategy consists of several stages, and a profusion of methods have been tried at every...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2016
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btw402